In my personal experience the really jam-heavy shows did not do it for me at all when I started listening to them. I didn't dislike the jams, but I just didn't really get what made them special either. So I gravitated mainly towards song-heavy shows with lots of prog, covers, or other zany gimmicks (like when they weave in and out of a different song for a whole set). Now of course I do get it and I love these sorts of shows. But it took a while for that style of jamming to click with me.
Ghost is one of those songs that goes in a different direction just about every time they play it. Probably unsurprisingly because of this it's become a pretty big fan favorite. There are tons of great versions of Ghost. One of those songs that changes to reflect where the band is at in any given era.
You Enjoy Myself is their signature song. It's always a winner.
Trey Anastasio never switches guitars during shows (which makes sense considering a show based on improv wouldn't be conducive to instrument changes) and almost exclusively plays his signature Languedoc. He's also one of those guitar players that has such a characteristic playing style that it doesn't matter what he does to the tone or what guitar he plays, it always sounds like him. So yeah there's some sameyness because of that for sure.