...although it's in DVD and may still be on Netflix or something.

It was animated, realistic, and featured a private American spy agency called 'ISIS' (that name got dropped eventually) operating under Mallory Archer, a former OSS officer in WWII. She had all sorts of connections, and her son, Sterling, was a skilled but incredibly oversexed and arrogant jerk was involved in most of it. It was hilarious, if inappropriate in almost every possible way.