1) Become a failed state like Libya after 'giving up' nuclear or WMD potential (precisely as Gaddafi did when offered 'incentives' by Bush/Cheney/Rice).

2) Or, become North Korea and you are immune from regime change wars launched by the West.

For the Iranians, the question of negotiations with the US at this point means negotiating their own demise - given they have already been relentlessly bombed. While the US may not be openly calling for regime change in Tehran, the reality is that many within Israel's top leadership, including Netanyahu, have.

https://www.zerohedge.com/geopolitical/israeli-official-confirms-rift-ceasefire-fails-trump-vowed-israel-wont-strike-after-he