I have driven in many parts of the USA including the big cities like NY,Boston LA and SF. Never a problem.
My biggest frustration in the US is how slow they are. Although to be fair the limits have increased from some of the pedestrian levels of 55 on rural highways to much the same as the UK. I recall using the I10 for much of the way from Tampa to New Orleans about 700 miles. Probably 20 years ago. I ached to put my foot down.
Another time driving to Palm Springs from Las Vegas I was inevitably stopped by a Trooper in the Megeve Desert area for a slightly enthusiastic speed! All went well when he asked me if I was a Limey. When I said Derbyshire it transpired that he had just married an English lady from Leicestershire. We had a great chat. That was it. The infraction was overlooked!!
I have got to say that driving in Europe I find Portugal is fine once you have worked out that they wait for a totally blind bend before overtaking. Italy can be frantic..... the idiots there are matched by our own home-grown half wits!!
The Cypriots can be a bit crackers even on the left.