I've had a higher than normal PSA and suffered a biopsy to make sure I didn't have cancer about 10 years ago. That was the norm back when my PSA was high. It still runs a bit high, but I guess that's normal for some folks. Now days they'll do a special MRI to look for suspected abnormalities and also know where to do the biopsy. I had 12 biopsy needle sticks to check my prostate. It is not a pleasant experience either. Sometimes the biopsy routine causes serious issues.

You'd think a POTUS would have had PSAs regularly enough to have detected something. I have 2 PSAs a year. Either he's got an extremely aggressive cancer or he wasn't checked as often as he should have been.