Conference Matchup Rules

The first four teams from any conference placed on the top four seed lines must be assigned to different regions (unless five or more teams appear on those seed lines).
Teams from the same conference:
Cannot meet before the regional final if they played three or more times during the regular season and conference tournament.
Cannot meet before the regional semifinal if they played twice.
May meet as early as the second round if they played once or not at all.
These restrictions may be relaxed if a conference has nine or more teams in the tournament.
Any principle may be relaxed if two or more of the conference’s teams are among the last four at-large teams in the First Four.
Top-seeded teams (first four lines) will not be placed where they would face a significant home-crowd disadvantage.